Pilocarpine
Adverse Effect: physical precipitation of pilocarpine Clinical Management: In general, ophthalmic products containing viscosity agents such as methylcellulose and polyvinyl alcohol are retained in the eye approximately twice as long as saline solutions. If pilocarpine hydrochloride and sodium sulfacetamide must be administered into the same eye, the dosing intervals should be separated as much as possible; a minimum interval of 15 to 20 minutes is recommended to prevent precipitation. |